goldenseal benefits dr axe

However, when present in excessive amounts, this fungus can cause vaginal yeast infections, oral thrush, skin rashes, and UTIs (24, 25). Ind J Med Res 1982;76(Suppl):71-76. You can also talk to your health care practitioner about what amount would be best for you and your particular health concern(s). 2008;83(1):61-69. II. B. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Pharmacognosy Res. Rabbani G. Mechanism and treatment of diarrhoea due to Vibrio cholerae and Escherichia coli: roles of drugs and prostaglandins. View abstract. Mikkelsen SL and Ash KO. However, research supporting its benefits is limited and generally weak. Therefore, people currently taking any type of medication should consult their healthcare provider before taking goldenseal (42, 49, 51). Only antibiotics can. Chin J Integr Med 2005;11:217-21. Liu CX, Xiao PG, and Liu GS. 2012;166(1):99-105. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. View abstract. Goldenseal might cause sleepiness and slowed breathing. Goldenseal can easily be found in tea or supplement form at your local health store or online. Although these results seem promising, theres currently no scientific proof that goldenseal produces the same effects. 1982;76 Suppl:83-88. Avoid putting unused and expired medicines down the drain or in the toilet. Sharda DC. If you suspect you're experiencing life-threatening side effects, seek immediate medical attention. View abstract. (11) For example, one in vitro study published in the journal Phytomedicine found that berberine inhibited the growth of breast cancer cells to a greater extent than doxorubicin (a chemotherapy drug). Clin Pharmacol Ther 2021;109(5):1342-52. View abstract. J Diarrhoeal Dis Res 1987;5(3):184-187. Palasuntheram C, Iyer KS, de Silva LB, and et al. J Indian M A 1970;54(1):22-24. Infantsparticularly newbornsmight get kernicterus from goldenseal. In contrast, the chemotherapy drug carmustine had a cell kill rate of only 43 percent. Despite its reputation as an agent that can mask illegal drugs in urine (pee), goldenseal doesn't seem to work with today's lab methods. Drug development and drug interactions | Table of substrates, inhibitors, and inducers. Goldenseal may pose risks in the following situations: Severe allergic reaction: Avoid goldenseal if you have a severe allergic reaction to it or its components (parts or ingredients). Diabetes: Berberine in goldenseal may affect your blood sugar levels. Native Americans historically used goldenseal for various health concerns including skin diseases, ulcer symptomsand gonorrhea. Li, H., Miyahara, T., Tezuka, Y., Namba, T., Suzuki, T., Dowaki, R., Watanabe, M., Nemoto, N., Tonami, S., Seto, H., and Kadota, S. The effect of kampo formulae on bone resorption in vitro and in vivo. Studies have demonstrated that berberine can reduce inflammation, boost the immune system and help fight cancer among many other benefits. Hajnicka, V., Kost'alova, D., Svecova, D., Sochorova, R., Fuchsberger, N., and Toth, J. 2008;91(4):694-701. It's thought to work through these chemicals. Aid digestive tract. Yuan, J., Shen, X. Pharmacy Times. 2005 - 2023 WebMD LLC, an Internet Brands company. For any of these concerns, a goldenseal mouth rinse can help by reducing inflammation and getting rid of any nasty bacteria. The dried underground stems (rhizomes) and roots of the plant are used to make teas, liquid extracts, tablets, and capsules as well as, Goldenseal is an excellent digestive aid since it is very bitter, which stimulates the appetite, aids digestion and encourages bile secretion. Chun YT, Yip TT, Lau KL, and et al. Here are the top 8. Tai, Y. H., Feser, J. F., Marnane, W. G., and Desjeux, J. F. Antisecretory effects of berberine in rat ileum. Its roots and leaves have been used in traditional medicine to treat a variety of ailments, especially those involving infections or inflammation (1). Therefore, more research is needed before strong conclusions can be made. Drug Metab Dispos 2007;35:240-5. Repeated administration of berberine inhibits cytochromes P450 in humans. View abstract. View abstract. Planta Med 2001;67:561-4. Shanbhag, S. M., Kulkarni, H. J., and Gaitonde, B. Khin, Maung U., Myo, Khin, Nyunt, Nyunt Wai, Aye, Kyaw, and Tin, U. Tai YH, Feser JF, Marnane WG, and et al. View abstract. Jiang XW, Zhang Y, Zhu YL, et al. Acetaldehyde-induced interleukin-1beta and tumor necrosis factor-alpha production is inhibited by berberine through nuclear factor-kappaB signaling pathway in HepG2 cells. Anis KV, Rajeshkumar NV, Kuttan R. Inhibition of chemical carcinogenesis by berberine in rats and mice. Most goldenseal found in commercial supplements is farmed. Keep in mind that newer drug testing methods are now able to detect the use of goldenseal in urine samples, reducing the likelihood of a false negative result on a drug test (17). View abstract. Effect of berberine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin in jejunum of pigs. It does so by converting toxic compounds into harmless substances in your liver or making sure theyre eliminated from your body through urine and sweat (15, 16). Chung, J. G., Chen, G. W., Hung, C. F., Lee, J. H., Ho, C. C., Ho, H. C., Chang, H. L., Lin, W. C., and Lin, J. G. Effects of berberine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adduct formation in human leukemia cells. 1989;10(2):174-176. Clinical assessement of CYP2D6-mediated herb-drug interactions in humans: Effects of milk-thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea. Phytomedicine. Li XB. Dried root supplements tend to be taken in a dosage ranging from 0.510 grams three times a day, whereas alcoholic tinctures and liquid extracts are typically taken in dosages of 0.310-mL dosages three times a day (1). Metabolism 2010;59(2):285-292. Studies on plant resources, pharmacology and clinical treatment with berbamine. Diabetes 2006;55(8):2256-2264. View abstract. 1982;35(2):471-475. According to animal research, berberine may also cause or worsen jaundice in newborns, possibly causing brain damage (4, 41, 42). Brown PN, Roman MC. Here is a list of 4 natural supplements that are just as effective as pharmaceutical drugs. However, more study is needed to verify goldenseal's usefulness for these applications.. Ind J Physiol & Pharmac 1971;15(3):111-132. . In fact, results from a small clinical trial suggest that topical berberine may relieve canker sore symptoms. Pharmacol Rev 2012;64(1):147-65. Be sure to follow relevant directions on product labels and consult a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, The Role Gut Bacteria Plays on the Overall Body. J Assoc Physicians India 1967;15:525-529. Winek CL, Elzein EO, Wahba WW, and et al. Available at: https://cms.herbalgram.org/BAP/BAB/BAP-BABs-Goldenseal-v4.pdf (Accessed 30 March 2017). Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. (. Zhang, H., Wei, J., Xue, R., Wu, J. D., Zhao, W., Wang, Z. Goldenseal can easily be found in tea or supplement form at your local health store or online. People using normal and appropriate doses of barberry don't generally report any negative side effects. Clin Exp.Pharmacol Physiol 2012;39(5):406-411. Khosla PG, Neeraj VI, Gupta SK, et al. How much goldenseal do I need to take to pass a drug test? Dong H, Zhao Y, Zhao L, Lu F. The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials. Inhibition of the bacterial surface protein anchoring transpeptidase sortase by isoquinoline alkaloids. The rats treated with berberine at 10 mg/kg had an 81 percent kill rate. Application of berberine on treating type 2 diabetes mellitus. Berberine tannate in acute diarrhoea. Lee, S., Lim, H. J., Park, H. Y., Lee, K. S., Park, J. H., and Jang, Y. Berberine inhibits rat vascular smooth muscle cell proliferation and migration in vitro and improves neointima formation after balloon injury in vivo. Taking goldenseal while taking losartan might change the effects of losartan. The key health benefits of goldenseal tea include its ability to boost the immune system, optimize digestion, detoxify the body, and protect cardiovascular health, among others. Goldenseal is an . That said, no studies can currently confirm whether these dosages are the most beneficial ones. Planta Med. Traditionally, Native Americans used goldenseal to treat a variety of health problems, including sore or itchy eyes, mouth ulcers, and even tuberculosis. 2012;68(2):213-217. doi: 10.1007%2Fs00228-011-1108-2. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. The idea of using it to alter drug test results came from the novel Stringtown on the Pike, by the pharmacist John Uri Lloyd. Goldenseal benefits the membrane for its antimicrobial and anti-inflammatory activity. View abstract. People currently taking medications should consult their healthcare provider before starting to take goldenseal. Journal of the Indian Medical Association 1967;48(1):1-11. Before taking goldenseal, contact your pharmacist or healthcare provider to help you safely achieve your health goals. are clickable links to these studies. Life Sciences 1992;50(8):pl-53-pl-58. Berberine in goldenseal may slightly lower blood glucose (sugar) in people with diabetes. Well-designed and long-term clinical trials are necessary to assess goldenseal's effectiveness and safety better. Z., Wang, S. K., Zhou, Z. X., Song, D. Q., Wang, Y. M., Pan, H. N., Kong, W. J., and Jiang, J. D. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Sriwilaijareon, N., Petmitr, S., Mutirangura, A., Ponglikitmongkol, M., and Wilairat, P. Stage specificity of Plasmodium falciparum telomerase and its inhibition by berberine. The bitter tasting roots of the plant are bright yellow or brown, twisted and wrinkled. Theres currently little to no research regarding the safety of goldenseal use in pregnant or breastfeeding women. View abstract. Planta Med 2013;79(6):437-46. Overview. For best results, follow the storage and handling recommendations outlined on your products packaging and make sure to discard products that have passed their expiration date. Phytotherapy Research 1991;5:228-230. (7), Some people also use it for stomach swelling (gastritis), peptic ulcers, ulcerative colitis, diarrhea, constipation, hemorrhoidsand intestinal gas. Hepatobiliary excretion of berberine. View abstract. Asher GN, Corbett AH, Hawke RL. View abstract. View abstract. Ivanovska N and Philipov S. Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids. You can also find disposal boxes in your area.Ask your pharmacist or healthcare provider if you have any questions about how to dispose of your medications or supplements. Examples of CYP3A4 substrates may include Zocor (simvastatin) for high cholesterol and cyclosporine or Prograf (tacrolimus) to prevent organ transplant rejection. However, little is known about its effects in children, other than that it may cause or worsen jaundice in newborns. Ann Trop Med Parasitol 1991;85:417-25. Winek CL, Elzein EO, Wahba WW, Feldman JA. Khin, Maung U. and Nwe, Nwe Wai. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Some medications are moved in and out of cells by pumps. Choudhry, V. P., Sabir, M., and Bhide, V. N. Berberine in giardiasis. Therefore, more research is needed. 2015;161:69-81. View abstract. [Antidiarrheal and anti-inflammatory effects of berberine]. Symptoms may include breathing difficulties, itchiness, and rash. Pharmacol Res. They also propose that berberine-containing plants may help prevent the herpes virus from replicating. 1988;11(4):253-260. View abstract. Clin Pediatr (Phila) 2007;46(9):831-834. A recent review of 12 studies found similar results in humans. Zhang Y, Li X, Zou D, et al. And CYP2D6 substrates may include a beta-blocker blood pressure medication called Bystolic (nebivolol) and a cough medication called Delsym (dextromethorphan). Goldenseal (Hydrastis canadensis), also known as orange root, yellow root or yellow puccoon, is a perennial herb belonging to the buttercup family, Ranunculaceae. B., Shah, K. M., and Shah, D. M. Berberine in treatment of diarrhoea. Iizuka, N., Miyamoto, K., Okita, K., Tangoku, A., Hayashi, H., Yosino, S., Abe, T., Morioka, T., Hazama, S., and Oka, M. Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines. Berberine in the treatment of diarrhoea of infancy and childhood. Therefore, talking to your healthcare provider about any supplements you plan to take and checking in about potential interactions with other supplements or medications is important. Native Americans also mixed the plant with bear grease for use as an insect repellent and they used the color-rich roots to dye clothing. However, there is no scientific evidence that has proven this rumor to be correct. Cheng, Z., Pang, T., Gu, M., Gao, A. H., Xie, C. M., Li, J. Y., Nan, F. J., and Li, J. Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK. Miyazaki, H., Shirai, E., Ishibashi, M., Hosoi, K., Shibata, S., and Iwanaga, M. Quantitation of berberine chloride in human urine by use of selected ion monitoring in the field desorption mode. Potential uses of goldenseal may include canker sores (ulcers in the mouth) and diabetes. However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. Therefore, more goldenseal-specific studies are needed. There are goldenseal products made by manufacturers in the United States. World J Gastroenterol. Berberine-containing plants like goldenseal may benefit your skin. Native Americans historically used goldenseal for various health concerns. Life Sci. View abstract. Food Chem Toxicol 1999;37(4):319-326. Bhide MB, Chavan SR, Dutta NK. Hou Q, Han W, Fu X. Pharmacokinetic interaction between tacrolimus and berberine in a child with idiopathic nephrotic syndrome. Digestive Support for Ailments like Bacterial Diarrhea and Gastritis. They can also ensure youre giving goldenseal a good trial at appropriate doses. Abourashed EA, Khan IA. View abstract. Am J Dis Child 1975;129:866. Well-designed studies in humans are necessary to evaluate goldenseal's effects on canker sores better. View abstract. Am J Vet Res 1982;43(9):1594-1598. This is largely in part due to berberine's antifungal and antibacterial properties that help to kill harmful microorganisms in the gut. Despite rumors, goldenseal will not cause a false-negative result for marijuana, cocaine, amphetamines, or any other illegal drugs. Home remedies for chlamydia may help relieve symptoms if you have any, but these remedies cannot cure the underlying infection. Tsai PL, Tsai TH. As such, storage, handling, and expiration dates are likely to vary. Echinacea is a plant thats also native to North America and traditionally used to treat infections, including the common cold (12). So, while looking at the label, ensure the goldenseal product is tested by a trusted third party, such as USP, ConsumerLab, or NSF. Breastfeeding: The NCCIH recommends against goldenseal while breastfeeding. Todays traditional uses of goldenseal have broadened to include the natural treatment and prevention of colds, respiratory tract infections, allergies, eye infections, digestive issues, canker sores, vaginitis, urinary tract infectionsand evencancer. View abstract. Skullcap is a flowering herb long used in traditional medicine. There is currently limited research to support goldenseal for any health benefits. Depending on which product you purchase, make sure to read the label for each brands recommended dosage. B., and Mehra, M. K. Effect of berberine chloride eye drops on clinically positive trachoma patients. Yamaura K, Shimada M, Nakayama N, Ueno K. Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats. A., Maciel, B. C., Secches, A. L., and Gallo, Junior L. Cardiovascular effects of berberine in patients with severe congestive heart failure. Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. Clinical trial of berberine in acute watery diarrhoea. With high dosages, possible side effects may include nausea, vomiting, diarrhea, dizziness, fainting, nosebleeds, low blood pressure, decreased heart rate, and decreased breathing. Keep in mind that natural products are not always necessarily safe and dosages can be important. These phytochemical alkaloids produce a powerful astringent effect on mucous membranes, reduce disease-causing inflammation and have antiseptic effects. Since storage instructions may vary for different natural products, carefully read the directions and packaging label on the container. Atherosclerosis 2006;186(1):29-37. Doggrell, S. A. Berberine--a novel approach to cholesterol lowering. At this time, its unclear what dosage of goldenseal would cause an overdose and what the effects of this overdose may be. Lin, C. C., Kao, S. T., Chen, G. W., Ho, H. C., and Chung, J. G. Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3. Discontinue use if any negative reactions like these occur. However, it is not clear if this interaction is serious enough to reduce the effects of oseltamivir. eases sore throat. Goldenseals potent properties are primarily due to the alkaloids berberine, canadine and hydrastine. If you take digoxin, talk to your healthcare provider before taking goldenseal. 2005 - 2023 WebMD LLC, an Internet Brands company. Goldenseal (Hydrastis canadensis L.) and its active constituents: A critical review of their efficacy and toxicological issues. It is available in: Follow the dosing guidelines on the packaging of the goldenseal product you are using. Goldenseal contains berberine, which might have . View abstract. Today . View abstract. (14), An animal model study published in the Journal of Lipid Research also demonstrates that the root extract is highly effective in regulation of the livers LDL (bad cholesterol) receptors and in reducing plasma cholesterol. European Journal of Clinical Pharmacology. View abstract. There are several different sources of goldenseal. Am Fam Physician. There's evidence that berberine may help lower high LDL, total cholesterol and high blood pressure levels. Zhongguo Zhong Yao Za Zhi 2011;36(21):3032-3035. There are very few studies on goldenseal. Hu, Y., Ehli, E. A., Kittelsrud, J., Ronan, P. J., Munger, K., Downey, T., Bohlen, K., Callahan, L., Munson, V., Jahnke, M., Marshall, L. L., Nelson, K., Huizenga, P., Hansen, R., Soundy, T. J., and Davies, G. E. Lipid-lowering effect of berberine in human subjects and rats. View abstract. View abstract. View abstract. For this reason, use caution with goldenseal. J AOAC Int. Goldenseal is a popular natural treatment for upper respiratory tract infections, including the common cold (6). Echinacea is the purple Kansas cone-flower. You can purchase a mouthwash that already contains goldenseal or you can easily make some mouthwash at home. View abstract. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. View abstract. View abstract. Yin, J., Xing, H., and Ye, J. Efficacy of berberine in patients with type 2 diabetes mellitus. Can J Microbiol 1969;15:1067-76. Side effects are rare but may include nausea, vomiting, and reduced liver function (42, 48, 49). Garber AJ. Currently, theres no evidence to suggest that combining goldenseal with echinacea offers any benefits beyond those associated with taking each on their own. Goldenseal is a perennial herb that's native to the eastern United States. The healing properties of goldthread aren't simply folkloric in nature. Atherosclerosis 2010;209(1):111-117. However, berberine supplements contain little to no hydrastine and canadine. Horn JR, Hansten PD. of North America growing from southern Quebec to northern Georgia and west to Missouri. Mol Pharmacol 2004;66(3):612-619. Remember also to check the label on the packaging. Its also used to treat skin disorders, lack of appetite, heavy or painful periods, sinus infections, indigestion, and other inflammatory or digestive disorders (1). Z., and Zhu, X. S. [Effect of berberine on transit time of human small intestine]. 1991;49(4):315-324. For instance, some of these studies suggest that vaginal chlamydia infections may be treated with berberine-containing douches, vaginal suppositories, or various types of oral goldenseal supplements (29). For example, you may experience the following: If you're having a severe allergic reaction or if any of your symptoms feel life-threatening, call 911 and get medical help right away. According to the World Health Organization (WHO), infections with C. jejuni are the most common cause of gastroenteritis (38). For the powdered root and rhizome, four to six grams per day in tablet or capsule form is sometimes recommended. View abstract. High-quality studies in humans are needed to assess goldenseal's effects on blood sugar better. Vik-Mo, H, Faria DB, Cheung W, and et al. Indian Pediatr. That said, few of these studies looked at the direct effects of goldenseal in humans, and no recent research can be found to support these older findings. Am J Chin Med 1999;27(2):265-275. Relationship between the clinical effects of berberine on severe congestive heart failure and its concentration in plasma studied by HPLC. Centers for Disease Control and Prevention. Arzneimittelforschung. Studies in mice and hamsters suggest that the berberine in goldenseal may help lower LDL (bad) cholesterol and triglyceride levels (43, 44). (16) Health products combining it withechinacea are very common and are created with immune system enhancement in mind. Overharvesting and loss of habitat have decreased the availability of wild goldenseal, but the plant is now grown commercially in the United States, especially in the Blue Ridge Mountains. J Ethnopharmacol. Wang, N., Feng, Y., Cheung, F., Chow, O. Y., Wang, X., Su, W., and Tong, Y. Evaluating the role of alternative therapy in burn wound management: randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second-degree burns. Scazzocchio F, Corneta MF, Tomassini L, Palmery M. Antibacterial activity of Hydrastis canadensis extract and its major isolated alkaloids. Although the results from this study seem promising, no human studies have directly examined the effect of goldenseal on UTIs or yeast infections to date. Because of this, some believe goldenseal may help hide the use of illegal drugs to pass a drug test (1). Rehman J, Dillow JM, Carter SM, et al. Influence of goldenseal root on the pharmacokinetics of indinavir. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. They are antimicrobial in that they kill bacteria, and they may even slow the growth of tumors. . Fukuda, K., Hibiya, Y., Mutoh, M., Koshiji, M., Akao, S., and Fujiwara, H. Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells. Taking goldenseal may change the way your body processes medication. (15). Its currently unknown whether berberine can pass from mother to baby through breastmilk (52). Hayasaka, S., Kodama, T., and Ohira, A. For this reason, results from berberine studies may not apply to goldenseal. National Institutes of Health Office of Dietary Supplements. Lau, C. W., Yao, X. Q., Chen, Z. Y., Ko, W. H., and Huang, Y. Cardiovascular actions of berberine. Berberine sulfate blocks adherence of Streptococcus pyogenes to epithelial cells, fibronectin, and hexadecane. ", National Organization for Rare Disorders: "Kernicterus. View abstract. View abstract. J Cardiovasc Pharmacol 1985;7(2):307-315. One study suggests that an herbal mouth rinse containing various herbs and goldenseal reduced the growth of bacteria responsible for dental plaque and gingivitis, a mild form of gum disease (31). Healthline Media does not provide medical advice, diagnosis, or treatment. Spit out and repeat. Neurochem.Res 2002;27(9):883-889. Short-term oral (by mouth) goldenseal use is likely safe for many adults. Bhowmick, S. K., Hundley, O. T., and Rettig, K. R. Severe hypernatremia and hyperosmolality exacerbated by an herbal preparation in a patient with diabetic ketoacidosis. People with high blood pressure, liver disease, or heart disease should consult their health care provider before taking it. Today, people use it for a variety of ailments. View abstract. But in general, keep your medications tightly closed and out of the reach of children and pets, ideally locked in a cabinet or closet. Yamaura K, Shimada M, Nakayama N, Ueno K. Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats. Continuous use should not exceed 21 days or three weeks, with a break of at least two weeks between each use. View abstract. What are jaundice and kernicterus?. boosts the immune system. treats skin and eye problems. Immune System There are quite a few active ingredients in goldenseal tea that prevent bacterial and viral infections, including a high concentration of alkaloids, protecting us against common respiratory and . Overdoses with goldenseal, however, might be similar to its potential common or severe side effects, which might be exaggerated or excessive.
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